Food Grade ε-Polylysine HCL – Bulk Natural Antimicrobial Preservative CAS 28211-04-3

ε-Polylysine HCL (Epsilon Polylysine Hydrochloride) is a high-efficiency broad-spectrum natural polypeptide preservative fermented from Streptomyces albulus strains. As the most popular clean label antimicrobial in 2026 global food industry, ε-Polylysine HCL effectively suppresses Gram-positive bacteria, Gram-negative bacteria, yeast and moulds, widely adopted in meat, seafood, dairy, beverage, instant rice, bakery and condiment production lines.

As a professional bulk ε-Polylysine HCL supplier based in Shandong China, we supply high-purity 99% ε-Polylysine powder with complete testing documents, stable large-volume FCL shipment, flexible MOQ and free trial samples for global food factories, ingredient distributors and cosmetic raw material suppliers. If you need factory price list, full TDS, COA and MSDS files of ε-Polylysine HCL, please send your demand to lucy@nihaobio.com.

food grade ε polylysine

What Is ε-Polylysine HCL?

ε-Polylysine HCL (CAS No. 28211-04-3) is water-soluble pale yellow powder produced via deep fermentation of Streptomyces albulus. Its molecular formula is C₆H₁₂N₂O (n=25-35), molecular weight ranges 3500–4700. Different from single Nisin preservative, ε-Polylysine HCL delivers full-spectrum antibacterial performance covering both negative and positive bacteria, with outstanding pH & thermal stability.
Our ε-Polylysine HCL strictly complies with GB1886.362-2022 national food safety standard, each batch finished with full microbial & heavy metal inspection to guarantee consistent quality for bulk export orders. You can check our another natural preservative product line via Food Grade Nisin Powder.

Complete Technical Specifications of Our Bulk ε-Polylysine HCL

 

Test ItemStandard Parameter
Product Nameε-Polylysine HCL / Epsilon Polylysine Hydrochloride
CAS Number28211-04-3
Purity≥99%
Production StrainStreptomyces albulus
AppearancePale yellow fine powder
Aqueous Solution pH (1%)4.0–6.5
Loss on Drying≤5.0 w/%
Ash Content≤3 w/%
Lead (Pb)≤1 mg/kg
Arsenic (As)≤0.5 mg/kg
Total Colony Count<1000 CFU/100g
Coliform Group<30 MPN/100g
SalmonellaNot detected in 25g
Thermal Stability120℃ 20min / 100℃ 30min / 80℃ 60min no activity loss
pH StabilityStable pH 1–13; long-term storage avoid pH<3 or pH>10
Shelf Life2 years under sealed cool & dry storage (0–20℃)
Standard Export Packing500g HDPE bottle, 10kg (20 bottles) per carton

Core Advantages of Our Bulk ε-Polylysine HCL

  • Full-spectrum natural antimicrobial

    Unlike Nisin only acting on Gram-positive bacteria, ε-Polylysine HCL inhibits E. coli, Staphylococcus aureus, Bacillus, yeast and moulds, perfect compound preservative matching clean label formulas.

  • Ultra-wide temperature & pH tolerance

    No activity loss after high-temperature sterilization 120℃ for 20 minutes, stable under pH 1–13, compatible with all acidic & neutral food systems.

  • Natural fermented, clean label friendly

    Non-toxic, fully biodegradable, no strange odor or food flavor change, fully replace sodium benzoate, potassium sorbate and other synthetic preservatives.

  • Low effective dosage & cost saving

    Small addition amount achieves long shelf-life extension, reduce raw material cost for large-scale food production.

  • Stable bulk factory supply for global export

    Rizhao base large fermentation workshop, support FCL full container bulk shipment, stable stock to avoid raw material shortage for food manufacturers.

  • Complete export certification documents

    Each shipment attached batch COA, microbial test report, MSDS, factory qualification file; support Halal, Kosher, FSSC 22000 certification application, smooth customs clearance for EU, USA, Southeast Asia, Middle East markets.

  • Flexible service for global buyers

    Free 10–500g test samples, custom OEM private label packaging, small trial order & large wholesale bulk MOQ support, professional technical formula guidance.

Main Application Fields of Food Grade ε-Polylysine HCL

Our ε-Polylysine HCL powder dissolves completely in water, widely applied across food, beverage, cosmetic & condiment industries:

1. Meat, Poultry & Vacuum Seafood

Cured meat, cooked poultry, vacuum seafood, sashimi, canned meat, fish fillets; effectively control spoilage bacteria during cold chain long-distance transportation.

2. Instant Rice, Noodles & Ready-to-Eat Meals

Convenient rice, wet noodles, sushi, cold dishes, prepared food; prevent mildew and acidification for long shelf life.

3. Dairy & Plant-Based Vegan Food

Fruit juice, plant beverage, coconut water, beer, grape fruit wine

Yogurt, processed cheese, plant milk, vegan meat substitutes, dairy desserts; meet global clean label plant food trends in 2026.

4. Beverage & Fermented Drinks

Fruit juice, plant beverage, coconut water, wine, fermented sauce; suppress yeast and spoilage bacteria without damaging drink taste.

5. Bakery, Snack & Condiments

Cakes, bread, salad dressing, chilled soup, pickles, canned vegetables; reduce calcium propionate usage for clean label packaging.

6.Cosmetic & Daily Care Raw Material

Natural preservative for facial cream, lotion, essence, shampoo, replacing synthetic parabens.

Recommended Dosage & Usage Guide

  • Standard dosage reference: 0.05–0.3 g/kg according to different food categories, follow GB1886.362-2022 national standard limit.
  • Feeding method: Dissolve ε-Polylysine HCL with clean water first, evenly mix into food raw materials before heating sterilization.
  • Compounding suggestion: Mix with Nisin, sodium lactate to strengthen antibacterial effect and lower total addition cost.
  • Special formula technical support: If you have complex production line demands, send your product formula to lucy@nihaobio.com for customized dosage scheme.

FAQ:

Q: What is the difference between ε-Polylysine HCL and regular Nisin preservative?

A: Nisin only inhibits Gram-positive bacteria and heat-resistant spores; ε-Polylysine HCL delivers broad-spectrum inhibition for Gram-negative, Gram-positive, yeast and moulds, wider application range, better performance for neutral & alkaline food systems. View our Nisin product page: https://nihaobio.com/natural-food-preservativese-nisin/.

Q: Is your ε-Polylysine HCL compliant with EU and FDA import standards?

A: Our ε-Polylysine HCL meets GB1886.362-2022, FDA GRAS and EU food additive requirements. We provide full COA, MSDS, heavy metal & microbial test reports for customs clearance. Email lucy@nihaobio.com to get scanned certification files.

Q: Can I get free test samples of ε-Polylysine HCL for formula testing?

A: We supply 10g–50g free samples for quality testing; clients only bear international shipping fees.

Q: Will you provide COA and MSDS documents?

A: Every shipment is attached with full batch COA and microbiology test reports. MSDS safety data sheet can be sent upon your request.

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